Characteristic Details
Chemical Name Dapoxetine Hydrochloride
Formulation Tablet
Strengths Available 30 mg, 60 mg
Indications Treatment of Premature Ejaculation
Pharmacokinetics Absorption: Rapid; Metabolism: Hepatic
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Pharmacokinetics

Dapoxetine 60 mg functions as a selective serotonin reuptake inhibitor (SSRI). Its absorption is rapid, peaking within 1-3 hours post-ingestion. The drug showcases a short half-life of about 19 hours, promoting quick systemic clearance. It is metabolized primarily by the liver, utilizing the cytochrome P450 system.

The hepatic metabolism involves multiple pathways, notably CYP2D6 and CYP3A4. Dapoxetine 60 mg is extensively bound to plasma proteins, which influences its distribution. Excretion occurs via the renal route, with inactive metabolites as the primary form of elimination.

Off-Label Uses

Though approved for premature ejaculation, Dapoxetine 30 mg finds off-label use in some cases. This includes treatments for anxiety disorders due to its SSRI mechanism. There are anecdotal reports suggesting utility in addressing depression, though this lacks formal endorsement.

Research into Dapoxetine’s broader applications continues, particularly in psychiatry. Some practitioners explore its potential in mood stabilization and other psychological concerns, albeit without official sanction.

Warnings & Precautions

Use of Dapoxetine 60 mg requires caution. Patients with cardiovascular conditions must avoid it due to its potential to induce orthostatic hypotension. Caution is advised in those with hepatic impairment due to its metabolism pathways.

Concomitant use with monoamine oxidase inhibitors (MAOIs) is contraindicated. Individuals with a history of syncope should be cautious. Alcohol may exacerbate side effects, thus avoidance is prudent.

Dapoxetine Disposal

Proper disposal of Dapoxetine 30 mg is crucial. Unused tablets should not be flushed or poured down drains. Return them to a take-back program if available. This reduces environmental contamination risks.

If no program exists, mix Dapoxetine with an unpalatable substance before sealing in a container for household waste disposal. This minimizes accidental ingestion or misuse.

Dapoxetine Signs and Symptoms of Overdose

Overdose symptoms may include nausea, dizziness, and tachycardia. In severe cases, serotonin syndrome is possible, characterized by agitation, hallucinations, and autonomic instability.

Emergency medical attention is essential if overdose is suspected. Supportive care focuses on stabilizing vital functions and addressing serotonin toxicity.

Purchasing Dapoxetine Without a Prescription

Acquiring Dapoxetine 60 mg without a prescription poses significant risks. It circumvents necessary medical evaluation and oversight. Dosage errors and potential drug interactions heighten dangers.

Online vendors offering prescription-free purchases may compromise product integrity. Risks of counterfeit medications and improper storage conditions threaten safety. Consulting healthcare professionals ensures informed usage.